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Advanced Accelerator Applications (AAA) is an innovative radiopharmaceutical company that develops, produces and commercializes diagnostic and therapeutic molecular nuclear medicine, or MNM, products.
AAA is at the forefront of developing predictive, preventive and personalized tools and procedures that have the potential to radically transform healthcare. Our path to accomplishing this goal is by merging therapeutic and diagnostic approaches to advance early detection, treatment, and monitoring of diseases, improving patient management.
AAA is developing a pipeline of theragnostic pairings for oncology indications. The company’s theragnostic platform involves radiolabeling a targeting molecule with either gallium Ga 68 for diagnostic use, or lutetium Lu 177 for therapy.
AAA’s first theragnostic pairing addresses neuroendocrine tumors, an orphan indication. The diagnostic part of this pairing is marketed as NETSPOT® in the US or SomaKit TOC™ in Europe. The therapeutic part, USAN: lutetium Lu 177 dotatate/INN: lutetium (177Lu) oxodotreotide (Lutathera®), is approved for use in Europe, and currently under review with the US Food and Drug Administration. Additional pairings in development target Gastrointestinal Stromal Tumors (GIST), and prostate and breast cancer.
AAA currently has 21 production and research & development facilities that manufacture both diagnostic and therapeutic Molecular Nuclear Medicine products, and over 550 employees in 13 countries (Belgium, Canada, France, Germany, Israel, Italy, the Netherlands, Poland, Portugal, Spain, Switzerland, the UK and the US).
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